Amplifying RI impact with a global perspective: a Regional Hubs model

Research Infrastructures, capacity building, Health, Infectious diseases, cryo Electron Microscopy, Super Resolution Microscopy, Integrative Regional Hubs Cooperation among Bioimaging & Structural Biology Research Infrastructures (RIs) from Latin America and Europe has steadily increased recently, e.g. via the EU-LAC ResInfra project. However, to have true impact on Health and long-lasting cooperation, even stronger and more tangible actions must be strategically planned. We now propose a bi-regional effort for capacity building, through staff hiring and exchange, focused on the creation/consolidation of Integrative Regional Hubs. Such Hubs are conceived as entry-to-mid-level RIs, well connected to high-end installations, with clear open facility access procedures and committed to open science. Regional Hubs shall accelerate the: (1) uptake of technology, (2) training of experts, (3) adoption of common RI best practices, (4) connection with local industry partners, and (5) efficient access to high-end RIs. The occurrence of global pandemics like Covid19 underscores the urgent need for globally concerted actions, combining biomedical expertise with state-of-the-art RIs, ensuring fast and effective responses. Key methodological aspects of this proposal include (i) the selection of Regional Hub sites, according to excellent science, engagement in biomedical research and long-standing record of open access to RIs. Eight RI partners in six LAC and EU countries, will contribute with their experience, also including two pan-European RI Consortia, maximising feasibility; and, (ii) a strong plan for training experts in advanced bioimaging technologies, following a well-designed network of interactions, staff exchange, visits and workshops. These exchanges will allow best practices and FAIR data management protocols to be shared, setting common standards. This model of Integrative Regional Hubs shall contribute to a global perspective in RI management.